Oncology Injection

Product Details:

ESENTRA 120 INJECTION contains Denosumab which belongs to the group of medicines called Monoclonal antibodies. It is used in adults to manage advanced cancer and to manage serious complications caused by bone metastasis (Ex. fractures, pressure on the spinal cord, radiation therapy, or surgery). It is also used to manage giant cell tumours of the bone, which cannot be managed by surgery, especially in adults whose bones have stopped growing. Symptoms include a visible mass and bone joints being affected (fracture, fluid buildup, limited movement, swelling, and pain in the joints).

Denosumab binds to RANKL, a protein that is essential for the formation, function, and survival of osteoclasts (the cells responsible for bone resorption). It inhibits osteoclast formation, function, and survival, thereby decreasing bone resorption and increasing bone mass and strength. Along with this management, your doctor might ask you to make certain lifestyle changes, such as maintaining good oral hygiene and quitting smoking. Your doctor may ask you to undergo a dental examination before you start the management. ESENTRA 120 INJECTION is not recommended for use in patients with hypocalcemia (low calcium levels in the blood) and unhealed wounds from oral surgery. Before receiving ESENTRA 120 INJECTION, inform your doctor if you have any problems with your mouth or teeth (poor dental health, gum disease, etc.).

ESENTRA 120 INJECTION is not recommended among women who are pregnant. Consult your doctor for advice before receiving ESENTRA 120 INJECTION if you are breast-feeding. ESENTRA 120 INJECTION is not recommended for children and adolescents under 18 years of age, except for adolescents with giant cell tumours of the bone whose bones have stopped growing. The most common side effects of receiving ESENTRA 120 INJECTION are pain in the bones, joints, and muscles, shortness of breath, diarrhea, hypophosphatemia (low phosphate level), and excessive sweating.

USES OF ESENTRA 120 INJECTION

It is used to manage:

Giant cell tumour of bone in adults whose bones have stopped growing

Complications caused by bone metastasis in advanced cancer (fracture, pressure on the spinal cord)

HOW ESENTRA 120 INJECTION WORKS

ESENTRA 120 INJECTION works to slow down bone destruction caused by cancer spreading to the bone (bone metastasis) or by giant cell tumour of bone.

DIRECTIONS FOR USE

ESENTRA 120 INJECTION will usually be administered to you subcutaneously (under the skin) by a doctor or nurse. You should also take calcium and vitamin D supplements while being managed with ESENTRA 120 INJECTION. Your doctor will decide the correct dose and duration for you depending on your age, body weight, and disease condition.

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Bortecad 2mg Injection is used in the treatment of multiple myeloma and mantle-cell lymphoma. It shows its working by stopping or slowing down the growth of cancer cells.

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