Evermil Tablets

Product Details:

Everolimus 5 mg tablets are a prescription medication used primarily in the treatment of various cancers and for the prevention of organ transplant rejection. It is a type of medication known as an mTOR kinase inhibitor.
Key Uses
Everolimus 5 mg may be prescribed for conditions including:
Advanced breast cancer (hormone receptor-positive, HER2-negative, in combination with exemestane, after other treatments have failed).
Advanced renal cell carcinoma (kidney cancer).
Progressive pancreatic neuroendocrine tumors (PNET).
Certain noncancerous tumors such as renal angiomyolipoma (kidney tumor) and subependymal giant cell astrocytoma (SEGA, a type of brain tumor) associated with tuberous sclerosis complex (TSC).
Prevention of organ rejection in patients who have received a kidney or liver transplant (used in combination with other immunosuppressants).
Mechanism of Action
Everolimus works by blocking a protein called the mammalian target of rapamycin (mTOR). This protein helps regulate cell growth and survival. By inhibiting mTOR, everolimus:
Stops the abnormal multiplication of cancerous cells, slowing tumor growth and spread.
Reduces blood supply to the tumor (angiogenesis inhibition).
Decreases the activity of the body's immune system, which helps prevent it from attacking a transplanted organ.
Important Considerations and Side Effects
Administration: The tablets should be swallowed whole with a glass of water, and not crushed, broken, or chewed. It should be taken at the same time each day, consistently with or without food.
Infection Risk: Everolimus can weaken the immune system, increasing the risk of serious infections. Patients should contact their doctor if they experience signs of infection like fever or chills.
Mouth Sores: Mouth ulcers or sores are a common side effect. Good oral hygiene is important during treatment.
Other Potential Side Effects: Common side effects include fatigue, breathlessness, cough, diarrhea, loss of appetite, dizziness, and high blood sugar levels (hyperglycemia).
Grapefruit: Avoid consuming grapefruit or grapefruit juice while on this medication, as it can interact with the drug's effects.
Sunlight Exposure: Everolimus may increase the risk of skin cancers, so patients should limit sun exposure and wear protective clothing/sunscreen.
This information is not a substitute for professional medical advice. A healthcare provider can provide guidance on the appropriate use, dosage, and potential side effects of everolimus 5 mg for a specific medical situation.